Sökresultat

Genetic and Environmental Risk Factors in the Development of Obesity Lifestyle behaviors and genetic variation have clear and distinguishable effects on obesity risk; however, the pattern of disease occurrence within and between populations that differ in their genetic and environmental underpinnings suggests obesity is caused in part by the interaction between adverse lifestyle behaviors and the

https://www.ludc.lu.se/education-training/theses/theses-2015/shafqat-ahmad - 2026-10-29

Metabolomics of weight loss and weight maintenance in obese humans The prevalence of obesity and obesity-related complications are increasing worldwide. Weight loss has shown to improve insulin sensitivity and decrease the risk of developing type 2 diabetes (T2D). Even so, little is known about how metabolites, other than glucoses are affected adter weight loss and weight maintenance treatment. Im

https://www.ludc.lu.se/education-training/theses/theses-2016/nina-geidenstam - 2026-10-29

Causes and consequences of hyperglycemia and glycosuria Type 2 diabetes is one of the world’s major challenges today. Over 400 million people around the globe are diagnosed with diabetes and the consequences to the individual patient and health care systems are significant. Diabetes is a chronic disease and the standard treatment including lifestyle changes, metformin and insulin is in many cases

https://www.ludc.lu.se/education-training/theses/theses-2016/emilia-ottosson-laakso - 2026-10-29

Genome-wide analysis of the DNA methylation landscapes in human tissues The prevalence of type 2 diabetes and obesity is rapidly increasing worldwide. Both pancreatic islets and adipose tissue play an important role in metabolic processes in humans, and dysfunction in these tissues may contribute to the pathogenesis of type 2 diabetes and obesity. Epigenetics is thought to be one of the processes

https://www.ludc.lu.se/education-training/theses/theses-2016/petr-volkov - 2026-10-29

Mechanisms of defective insulin secretion in type 2 diabetes Defective insulin secretion from the pancreatic B-cells is a central feature in type 2 diabetes (T2D). There is a strong hereditary component in type T2D, but the underlying pathophysiology remains largely unknown. This thesis uses a combination of gene network analysis and cell-physiological techniques to explore the genetic and cellula

https://www.ludc.lu.se/education-training/theses/theses-2013/taman-mahdi-hamed - 2026-10-29

Development of protocols for metabolomics in biomedical research using chemometrics Metabolomics is a rapidly growing research field. It aims for quantification of all the metabolites in a biological sample such as plasma, saliva, cerebrospinal fluid or cells. Because the metabolite levels in a biological sample are the end result of the regulatory processes in cells, metabolomics is a very powerf

https://www.ludc.lu.se/education-training/theses/theses-2010/anders-danielsson - 2026-10-29

Folate - associations with breast cancer depending on intake, metabolism, genetic variation and estrogen receptor status Folate is a B-vitamin that may influence cancer development via its role as methyl donor for DNA synthesis and methylation. Plant foods contain many bioactive compounds including folate and fiber. Results from the Malmö Diet and Cancer (MDC) cohort indicate lower breast cancer r

https://www.ludc.lu.se/education-training/theses/theses-2010/ulrika-ericson - 2026-10-29

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https://www.ludc.lu.se/research-0/epigenetics-and-diabetes/previous-group-members/annika-lundstig - 2026-10-29

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https://www.ludc.lu.se/research-0/epigenetics-and-diabetes/previous-group-members/anders-h-olsson - 2026-10-29

I am Diana and I am from Spain. I am currently performing my master studies in Biomedicine at Lund University, which I started in September 2015. Before moving to Sweden, I completed my bachelor´s degree in Biochemistry at the University of Valencia and I also went to Norway for one year in an Erasmus exchange. Right now I am performing my master thesis: This project aims to understand the role of

https://www.ludc.lu.se/research-0/molecular-metabolism/group-members/diana-grajales-abellan-student - 2026-10-29

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https://www.ludc.lu.se/research-0/neuroendocrine-cell-biology/group-members - 2026-10-29

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https://www.ludc.lu.se/research-0/genomics-diabetes-and-endocrinology/affiliated-researchers - 2026-10-29

Researcher profiles

https://www.ludc.lu.se/researcher-profiles - 2026-10-29

Substances in the food we eat stress the insulin-producing beta cells to death. Albert Salehi conducts research on how the beta cells function, and believes in new anti-diabetic drugs that can protect the beta cells and prevent type 2 diabetes. After studying pharmacology at Linköping University, Albert Salehi wanted to go on to study medicine. By chance he came into contact with Professor Ingemar

https://www.ludc.lu.se/beta-cells-diet-and-new-drugs - 2026-10-29

The focus of Hindrik Mulder’s research is on the metabolism of insulin-producing beta cells. The question he studies is what goes wrong in type 2 diabetes: why do the insulin-producing beta cells fail? Why are they no longer able to release as much insulin as is needed to keep blood sugar levels under control? “The cells’ powerhouses – mitochondria – play a key role in this. The mitochondria give

https://www.ludc.lu.se/dantes-circles-hell-academic-freedom - 2026-10-29